Prashant Mali, PhD

2022 AIMBE Fellow

2022 AIMBE Fellow

Election to the AIMBE College of Fellows is among the highest professional distinctions accorded to a medical and biological engineer. The College of Fellows is comprised of the top two percent of medical and biological engineers. College membership honors those who have made outstanding contributions to “engineering and medicine research, practice, or education” and to “the pioneering of new and developing fields of technology, making major advancements in traditional fields of medical and biological engineering, or developing/implementing innovative approaches to bioengineering education.”

AIMBE Fellows are among the most distinguished medical and biological engineers including 3 Nobel Prize laureates, 18 Fellows having received the Presidential Medal of Science and/or Technology and Innovation, and 201 also inducted to the National Academy of Engineering, 101 inducted to the National Academy of Medicine and 45 inducted to the National Academy of Sciences.

Dr. Prashant Mali

Mali is being recognized for his pioneering contributions to genome editing and enabling gene and cell based human therapeutics. He has helped develop CRISPRs and ADARs as powerful tools for DNA and RNA editing, respectively. Recently, Mali’s lab developed a new RNA editing technology that could make it simpler to repair disease-causing mutations in RNA without compromising precision or efficiency. The technology is the first proof-of-concept in vivo RNA editing for treating genetic diseases using ADARs that are native to cells. His lab has also developed a CRISPR-based gene therapy for chronic pain, which could offer a safer and non-addictive alternative to opioids. The Mali lab has a strong translational focus with several gene therapy technologies licensed to and being further developed by startup companies including Navega Therapeutics and Shape Therapeutics, both co-founded by Mali.