News

'MUSIC Map' Reveals Some Brain Cells Age Faster and Are More Prevalent in Alzheimer's

May 14, 2024

'MUSIC Map' Reveals Some Brain Cells Age Faster and Are More Prevalent in Alzheimer's

UC San Diego engineers have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex. The discoveries were made possible by a new technique called MUSIC (multinucleic acid interaction mapping in single cells), which allows researchers to peek inside individual brain cells and map out interactions between chromatin and RNA. Full Story


UC San Diego Researchers Honored as Prebys Research Heroes

May 2, 2024

UC San Diego Researchers Honored as Prebys Research Heroes

Three UC San Diego researchers, including two bioengineers, have been named Prebys Research Heroes by the San Diego-based Conrad Prebys Foundation. These researchers have received grants of $500,000 each to support their research focused on advancing health care and medical discoveries. Full Story


Biodegradable 'Living Plastic' Houses Bacterial Spores That Help It Break Down

April 30, 2024

Biodegradable 'Living Plastic' Houses Bacterial Spores That Help It Break Down

A new type of bioplastic could help reduce the plastic industry’s environmental footprint. Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle. Full Story