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Making recombinant-protein drugs cheaper

April 23, 2020

Making recombinant-protein drugs cheaper

By cleaning up mammalian cell lines that produce recombinant-protein drugs, researchers forge a path to purer, cheaper drugs that treat cancer, arthritis and other complex diseases Full Story


Bioengineers inducted into prestigious biomedical institution

April 8, 2020

Bioengineers inducted into prestigious biomedical institution

Two researchers at the Jacobs School of Engineering were inducted into the College of Fellows of the American Institute for Medical and Biological Engineering. The College of Fellows is comprised of the top 2 percent of medical and biological engineers in the country. Full Story


Discovery of new biomarker in blood could lead to early test for Alzheimer's disease

March 31, 2020

Discovery of new biomarker in blood could lead to early test for Alzheimer's disease

UC San Diego researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer’s disease. The work could lead to the development of a blood test to identify individuals who will develop the disease years before they show symptoms. Full Story


UC San Diego Engineers and Doctors Team Up to Retrofit and Build Ventilators

March 26, 2020

UC San Diego Engineers and Doctors Team Up to Retrofit and Build Ventilators

Even as university campuses close across the nation in an effort to slow the spread of the novel coronavirus, a team of engineers and physicians at the University of California San Diego is rapidly developing simple, ready-to-use ventilators to be deployed if the need arises.The project kick-started several weeks ago when news started to trickle in that communities in Northern Italy with widespread COVID-19 were in dire straits.“One of the biggest things we heard was that there weren’t enough ventilators to treat all of the patients coming into the hospitals,” said James Friend, a professor in the Department of Mechanical and Aerospace Engineering and the Department of Surgery at UC San Diego. “It’s clear that if we’re not careful, we might end up in the same situation.” Full Story


Making cell modeling more realistic

March 17, 2020

Making cell modeling more realistic

UC San Diego researchers have developed a computational tool that makes modeling and simulation of complex cellular processes more true to life. The tool, dubbed GAMer 2, simplifies the process of using realistic cell geometries in mathematical models. Full Story


Undergraduate students bring Intranet to rural Ghanaian school

March 16, 2020

Undergraduate students bring Intranet to rural Ghanaian school

A team of undergraduates, who are part of the Global Ties program at the UC San Diego Jacobs School of Engineering, developed a self-sustaining and scalable computer server and intranet system. The system will allow teachers at the Semanhyiya American School (SAS) in the rural village of Senase, Ghana, to download Internet pages and educational materials that students can access anytime at school—even when there is no Internet.  Full Story


UC San Diego synthetic biologists redesign the way bacteria 'talk' to each other

March 4, 2020

UC San Diego synthetic biologists redesign the way bacteria 'talk' to each other

Bioengineers at the University of California San Diego have redesigned how harmless E. coli bacteria “talk” to each other. The new genetic circuit could become a useful new tool for synthetic biologists who, as a field, are looking for ways to better control the bacteria they engineer to perform all sorts of tasks, including drug delivery, bioproduction of valuable compounds, and environmental sensing. Full Story


Scientists Design Way to Use Harmless Bacteria to Detect Heavy Metals in Drinking Water

February 27, 2020

Scientists Design Way to Use Harmless Bacteria to Detect Heavy Metals in Drinking Water

A team from UC San Diego and the San Diego startup Quantitative BioSciences has a new approach to continuous monitoring of heavy metal contamination in drinking water using bacteria as sensors of contamination. The team recently published their advances in the journal Proceedings of the National Academy of Science (PNAS). Full Story


Controlling CAR T cells with light selectively destroys skin tumors in mice

February 19, 2020

Controlling CAR T cells with light selectively destroys skin tumors in mice

UC San Diego bioengineers have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the researchers controlled the cells to destroy skin tumors in mice without harming healthy tissue. Full Story


Jacobs School faculty, student, staff honored with Inclusive Excellence Awards

February 4, 2020

Jacobs School faculty, student, staff honored with Inclusive Excellence Awards

Three members of the Jacobs School of Engineering community were awarded 2020 Inclusive Excellence Awards for their outstanding contributions toward increasing diversity at all levels at UC San Diego.  Full Story


Algae Shown to Improve Gastrointestinal Health

February 3, 2020

Algae Shown to Improve Gastrointestinal Health

A widespread, fast-growing plant called Chlamydomonas reinhardtii is famous in scientific laboratories due to its position as the world’s most exhaustively studied algae. Researchers at the University of California San Diego recently completed the first study examining the effects of consuming C. reinhardtii and demonstrated that the algae improves human gastrointestinal issues associated with irritable bowel syndrome (IBS) such as diarrhea, gas and bloating. Results of the project are published in the Journal of Functional Foods. Full Story


Assessing 'stickiness' of tumor cells could improve cancer prognosis

February 3, 2020

Assessing 'stickiness' of tumor cells could improve cancer prognosis

Researchers led by UC San Diego built a device that sorts and separates cancer cells from the same tumor based on how “sticky” they are. They found that less sticky cells migrate and invade other tissues more than their stickier counterparts, and have genes that make tumor recurrence more likely. Full Story