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Borderzone Breakthrough: A New Source of Cardiac Inflammation

August 28, 2024

Borderzone Breakthrough: A New Source of Cardiac Inflammation

In the Aug. 28, 2024 issue of Nature, researchers from University of California San Diego in the laboratory of Dr. Kevin King, associate professor of bioengineering and medicine, and a cardiologist at the Sulpizio Cardiovascular Center, report the discovery of a novel mechanism of cardiac inflammation that may expand therapeutic opportunities to prevent heart attacks from becoming heart failure. Full Story


Closing the RNA Loop Holds Promise for More Stable, Effective RNA Therapies

August 26, 2024

Closing the RNA Loop Holds Promise for More Stable, Effective RNA Therapies

New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by UC San Diego researchers. The advance holds promise for a range of diseases, offering a more enduring alternative to existing RNA therapies, which often suffer from short-lived effectiveness in the body.   Full Story


Simulations from Atom to Organ Reveal Novel Treatment Mechanisms for Heart Failure

August 19, 2024

Simulations from Atom to Organ Reveal Novel Treatment Mechanisms for Heart Failure

A team of researchers from UC San Diego has developed the first multiscale computational model to simulate the therapeutic mechanisms of a drug candidate for heart failure from the atomic level to the organ system scale. Full Story


18 New Endowed Chairs Created at the UC San Diego Jacobs School of Engineering

August 6, 2024

18 New Endowed Chairs Created at the UC San Diego Jacobs School of Engineering

The UC San Diego Jacobs School of Engineering has created 18 new endowed chairs, empowering a world-class cohort of faculty to explore new and innovative research directions. These endowed chairs have been made possible through the generous and visionary philanthropy of Irwin and Joan Jacobs. Full Story


Precision Oncology via Artificial Intelligence on Cancer Biopsies

July 31, 2024

Precision Oncology via Artificial Intelligence on Cancer Biopsies

A new AI tool developed by UC San Diego bioengineers, oncologists and medical researchers could get patients with breast & ovarian cancers started on the best treatment sooner—without spending thousands of dollars on genomic testing. Full Story


Diatom Surprise Could Rewrite the Global Carbon Cycle

July 17, 2024

Diatom Surprise Could Rewrite the Global Carbon Cycle

When it comes to diatoms that live in the ocean, new research suggests that photosynthesis is not the only strategy for accumulating carbon. Instead, these single-celled plankton are also building biomass by feeding directly on organic carbon in wide swaths of the ocean. These new findings from a team led by UC San Diego researchers could lead to reduced estimates regarding how much carbon dioxide diatoms pull out of the air via photosynthesis, which in turn, could alter our understanding of the global carbon cycle, which is especially relevant given the changing climate.     Full Story


How Your Sleep Patterns Change Can Tell You About Your Health

June 20, 2024

How Your Sleep Patterns Change Can Tell You About Your Health

Your sleep tracker might give you information about more than just your sleep–specifically, it might give you information about chronic conditions such as diabetes and sleep apnea, and illnesses such as COVID-19. This is one of the findings of a study that analyzed data from 5 million nights of sleep across roughly 33,000 people.  Full Story


UC San Diego Jacobs School Of Engineering Rises In Latest U.S. News And World Report Rankings Of Best Engineering Schools

June 18, 2024

UC San Diego Jacobs School Of Engineering Rises In Latest U.S. News And World Report Rankings Of Best Engineering Schools

The UC San Diego Jacobs School of Engineering has ranked the #11 best in the nation in the influential U.S. News & World Report Rankings of Best Engineering Schools. This #11 ranking is up from #12 last year. Full Story


An Innovative Way to Detect Bacteria Fast in Pediatric Blood Samples

June 14, 2024

An Innovative Way to Detect Bacteria Fast in Pediatric Blood Samples

Researchers have demonstrated that a new technology could quickly and accurately diagnose bloodstream infections. The study findings were reported at ASM Microbe, the annual meeting of the American Society for Microbiology.    Full Story


Jacobs School of Engineering 2024 Award of Excellence Recipients

June 14, 2024

Jacobs School of Engineering 2024 Award of Excellence Recipients

Six undergraduate students were selected from among their peers to receive an Award of Excellence from their academic department in recognition of their outstanding academic, leadership and community contributions. Full Story


'MUSIC Map' Reveals Some Brain Cells Age Faster and Are More Prevalent in Alzheimer's

May 14, 2024

'MUSIC Map' Reveals Some Brain Cells Age Faster and Are More Prevalent in Alzheimer's

UC San Diego engineers have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex. The discoveries were made possible by a new technique called MUSIC (multinucleic acid interaction mapping in single cells), which allows researchers to peek inside individual brain cells and map out interactions between chromatin and RNA. Full Story


UC San Diego Researchers Honored as Prebys Research Heroes

May 2, 2024

UC San Diego Researchers Honored as Prebys Research Heroes

Three UC San Diego researchers, including two bioengineers, have been named Prebys Research Heroes by the San Diego-based Conrad Prebys Foundation. These researchers have received grants of $500,000 each to support their research focused on advancing health care and medical discoveries. Full Story


Biodegradable 'Living Plastic' Houses Bacterial Spores That Help It Break Down

April 30, 2024

Biodegradable 'Living Plastic' Houses Bacterial Spores That Help It Break Down

A new type of bioplastic could help reduce the plastic industry’s environmental footprint. Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle. Full Story


Innovative Microscopy Demystifies Metabolism of Alzheimers Disease

April 23, 2024

Innovative Microscopy Demystifies Metabolism of Alzheimers Disease

Bioengineers and neuroscientists at UC San Diego have deployed state-of-the art imaging techniques to study the metabolism driving Alzheimer’s disease; results suggest new treatment strategies Full Story


Acting Student and Bioengineering Alumna Awarded Soros Fellowship for New Americans

April 17, 2024

Acting Student and Bioengineering Alumna Awarded Soros Fellowship for New Americans

Riyam Al Msari, an undergraduate bioengineering alumna from Iraq, is one of 30 recipients of the 2024 Paul & Daisy Soros Fellowship for New Americans. The merit-based program for immigrants and children of immigrants awards up to $90,000 to support each fellow’s graduate studies.  Full Story


UC San Diego Engineers Inducted Into 2024 Class of the AIMBE College of Fellows

March 25, 2024

UC San Diego Engineers Inducted Into 2024 Class of the AIMBE College of Fellows

Two engineering professors at the University of California San Diego Jacobs School of Engineering were inducted into the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). Professors Ludmil Alexandrov and Sheng Xu were among the 162 new AIMBE Fellows who were recognized at a ceremony during the AIMBE Annual Event on March 25. Full Story


New Imaging Tool Advances Study of Lipid Biology

March 14, 2024

New Imaging Tool Advances Study of Lipid Biology

From fruit flies to humans, there are many, many different types and subtypes of lipids operating at the same time within any living organism. While we know that lipid molecules play myriad different roles in health, aging and disease; researchers currently struggle to uncover the fine details of these roles – details which could unlock cures, extend the human healthspan, and solve mysteries of aging. A study led by bioengineers at the University of California San Diego marks a significant step forward in this critical area of lipid research. Full Story


This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart

March 6, 2024

This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart

An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study published March 6 in Journals of the American College of Cardiology: Basic to Translational Science.  Full Story


Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA

February 21, 2024

Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.    Full Story


Five Cutting-edge Advances in Biomedical Engineering and Their Applications in Medicine

February 21, 2024

Five Cutting-edge Advances in Biomedical Engineering and Their Applications in Medicine

Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.  These are the five research areas where the field of biomedical engineering has the potential to achieve tremendous impact on the field of medicine. Full Story