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'MUSIC Map' Reveals Some Brain Cells Age Faster and Are More Prevalent in Alzheimer’s

May 14, 2024

'MUSIC Map' Reveals Some Brain Cells Age Faster and Are More Prevalent in Alzheimer’s

UC San Diego engineers have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex. The discoveries were made possible by a new technique called MUSIC (multinucleic acid interaction mapping in single cells), which allows researchers to peek inside individual brain cells and map out interactions between chromatin and RNA. Full Story


UC San Diego Researchers Honored as Prebys Research Heroes

May 2, 2024

UC San Diego Researchers Honored as Prebys Research Heroes

Three UC San Diego researchers, including two bioengineers, have been named Prebys Research Heroes by the San Diego-based Conrad Prebys Foundation. These researchers have received grants of $500,000 each to support their research focused on advancing health care and medical discoveries. Full Story


Biodegradable 'Living Plastic' Houses Bacterial Spores That Help It Break Down

April 30, 2024

Biodegradable 'Living Plastic' Houses Bacterial Spores That Help It Break Down

A new type of bioplastic could help reduce the plastic industry’s environmental footprint. Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle. Full Story


Innovative Microscopy Demystifies Metabolism of Alzheimers Disease

April 23, 2024

Innovative Microscopy Demystifies Metabolism of Alzheimers Disease

Bioengineers and neuroscientists at UC San Diego have deployed state-of-the art imaging techniques to study the metabolism driving Alzheimer’s disease; results suggest new treatment strategies Full Story


Acting Student and Bioengineering Alumna Awarded Soros Fellowship for New Americans

April 17, 2024

Acting Student and Bioengineering Alumna Awarded Soros Fellowship for New Americans

Riyam Al Msari, an undergraduate bioengineering alumna from Iraq, is one of 30 recipients of the 2024 Paul & Daisy Soros Fellowship for New Americans. The merit-based program for immigrants and children of immigrants awards up to $90,000 to support each fellow’s graduate studies.  Full Story


UC San Diego Engineers Inducted Into 2024 Class of the AIMBE College of Fellows

March 25, 2024

UC San Diego Engineers Inducted Into 2024 Class of the AIMBE College of Fellows

Two engineering professors at the University of California San Diego Jacobs School of Engineering were inducted into the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). Professors Ludmil Alexandrov and Sheng Xu were among the 162 new AIMBE Fellows who were recognized at a ceremony during the AIMBE Annual Event on March 25. Full Story


New Imaging Tool Advances Study of Lipid Biology

March 14, 2024

New Imaging Tool Advances Study of Lipid Biology

From fruit flies to humans, there are many, many different types and subtypes of lipids operating at the same time within any living organism. While we know that lipid molecules play myriad different roles in health, aging and disease; researchers currently struggle to uncover the fine details of these roles – details which could unlock cures, extend the human healthspan, and solve mysteries of aging. A study led by bioengineers at the University of California San Diego marks a significant step forward in this critical area of lipid research. Full Story


This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart

March 6, 2024

This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart

An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study published March 6 in Journals of the American College of Cardiology: Basic to Translational Science.  Full Story


Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA

February 21, 2024

Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.    Full Story


Five Cutting-edge Advances in Biomedical Engineering and Their Applications in Medicine

February 21, 2024

Five Cutting-edge Advances in Biomedical Engineering and Their Applications in Medicine

Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.  These are the five research areas where the field of biomedical engineering has the potential to achieve tremendous impact on the field of medicine. Full Story


Renowned UC San Diego Microbiome Pioneer Rob Knight Elected to the National Academy of Engineering

February 7, 2024

Renowned UC San Diego Microbiome Pioneer Rob Knight Elected to the National Academy of Engineering

Rob Knight, a University of California San Diego professor and international leader in the study of the roles microbes play in human health and disease and the functioning of ecosystems, has been elected to the National Academy of Engineering–the highest professional recognition afforded to engineers and computer scientists. On Feb. 6, 2024, the National Academy of Engineering recognized Knight for his pioneering leadership and “for understanding microbiomes and their application to healthcare and sustainability.” Full Story


Researchers Uncover Surprising Link Between Body Temperature and Depression

February 5, 2024

Researchers Uncover Surprising Link Between Body Temperature and Depression

People with depression have higher body temperatures, a finding that supports nascent research suggesting a mental health benefit to lowering the temperatures of those with the disorder, a new research team that includes scientists at the University of California San Diego found.   Full Story


Bioengineer Named NAS New Voice for Emerging STEM Leaders

February 1, 2024

Bioengineer Named NAS New Voice for Emerging STEM Leaders

Kiana Aran, a professor of bioengineering and medicine at UC San Diego, has been named to the National Academies of Sciences, Engineering, and Medicine’s 2024 New Voices in Sciences, Engineering, and Medicine program. New Voices aims to expand the diversity of expertise engaged in the work of the National Academies while developing a network of U.S. leaders to address national and global challenges. Full Story


AI Harnesses Tumor Genetics to Predict Treatment Response

January 18, 2024

AI Harnesses Tumor Genetics to Predict Treatment Response

In a groundbreaking study published on January 18, 2024, in Cancer Discovery, computer scientists, bioengineers and physicians at UC San Diego leveraged a machine learning algorithm to tackle one of the biggest challenges facing cancer researchers: predicting when cancer will resist chemotherapy. Full Story


Noninvasive Test for Embryo Quality Could Streamline Fertility Treatment

January 10, 2024

Noninvasive Test for Embryo Quality Could Streamline Fertility Treatment

Bioengineers and physicians at UC San Diego have discovered a noninvasive approach that can be used to better predict the quality of lab-grown embryos, potentially streamlining IVF treatment. Full Story


2023 Jacobs School Highlights

December 19, 2023

2023 Jacobs School Highlights

It was another busy year at the Jacobs School of Engineering, as our students, faculty, staff, and industry and community partners worked together to pursue engineering and computer science for the public good. From research breakthroughs in robotics, AI and healthcare, to launching new centers for microelectronics and computing, here are just a few highlights from 2023.   Full Story


UC San Diego Engineering Professors Elected Fellows of National Academy of Inventors

December 12, 2023

UC San Diego Engineering Professors Elected Fellows of National Academy of Inventors

Eric Fullerton, a professor in the Department of Electrical and Computer Engineering, and Prashant Mali, a professor in the Shu Chien-Gene Lay Department of Bioengineering, have been named 2023 Fellows of the National Academy of Inventors. Full Story


The science of sugar metabolism

November 21, 2023

The science of sugar metabolism

Bioengineernig professor Lingyan Shi and her team are on the cutting edge of the science of sugar metabolism (and the science of fat metabolism).  In particular, they were just awarded $1.97M in NIH grant funding to build an imaging platform to visualize sugar metabolic activities in aging and in disease. Full Story


UC San Diego Researchers Receive Close to $10M from California Stem Cell Research Agency

November 20, 2023

UC San Diego Researchers Receive Close to $10M from California Stem Cell Research Agency

Two researchers at UC San Diego received close to $10 million in grants from the California Institute of Regenerative Medicine. Full Story


Jacobs School researchers named most highly cited in the world

November 17, 2023

Jacobs School researchers named most highly cited in the world

Yet again, 16 faculty and researchers at the UC San Diego Jacobs School of Engineering were named among the world’s most influential in their fields in this year’s Clarivate listing of Most Highly Cited Researchers in the World. Full Story