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Mapping mutation 'hotspots' in cancer reveals new drivers and biomarkers

February 9, 2022

Mapping mutation 'hotspots' in cancer reveals new drivers and biomarkers

UC San Diego researchers have identified a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome. These mutation clusters contribute to the progression of about 10% of human cancers and can be used to predict patient survival. Full Story


New drug screening method answers why Alzheimer's drugs fail, suggests new targets

January 27, 2022

New drug screening method answers why Alzheimer's drugs fail, suggests new targets

A study led by UC San Diego sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing the disease. The researchers identify new targets for drug development and present a new method to screen drugs for treating Alzheimer's disease. Full Story


Introducing the second cohort of Racial Equity Fellows

January 10, 2022

Introducing the second cohort of Racial Equity Fellows

Seven UC San Diego Jacobs School of Engineering students have been selected to serve as Racial Equity Fellows. In this role, they will act as student advocates on the Jacobs School Student and Faculty Racial Equity Task Force, each bringing their demonstrated interest in diversity, equity and inclusion to the Task Force. Full Story


Our 2021 Research Headlines

December 20, 2021

Our 2021 Research Headlines

From research into new ways to detect and preventCOVID-19, to new treatments for heart conditions and technology to combat natural disasters and climate change, it has been a busy year at the Jacobs School of Engineering. Here is a snapshot of research that made headlines this year, thanks to the dedicated work of our faculty, graduate and undergraduate student researchers, and staff   Full Story


Developing Sex-specific Treatments for Heart Disease

December 2, 2021

Developing Sex-specific Treatments for Heart Disease

Heart diseases progress differently in men and women, yet treatments remain strikingly similar. UC San Diego bioengineering professor Brian Aguado aims to change that by studying sex-specific differences in disease, and developing new biomaterial treatments. Full Story


10 Jacobs School faculty among 2021 list of most highly cited researchers in the world

November 30, 2021

10 Jacobs School faculty among 2021 list of most highly cited researchers in the world

Ten professors at the University of California San Diego Jacobs School of Engineering are among the world’s most influential researchers in their fields. The professors, Ludmil Alexandrov, Trey Ideker, Rob Knight, Prashant Mali, Ying Shirley Meng, Shyue Ping Ong, Bernhard O. Palsson, Joseph Wang, Sheng Xu and Liangfang Zhang, are amone 51 professors and researchers at UC San Diego named in the prestigious list of Highly Cited Researchers in 2021. Full Story


Graduate students honored as Siebel Scholars

September 23, 2021

Graduate students honored as Siebel Scholars

Five graduate students working at the interface of engineering and medicine have been honored as 2022 Siebel Scholars. They are pursuing graduate degrees in bioengineering, electrical engineering, nanoengineering, and bioinformatics, all with a focus on advancing human health.    Full Story


Three Jacobs School undergraduate programs ranked in nation's top 10

September 14, 2021

Three Jacobs School undergraduate programs ranked in nation's top 10

Three undergraduate academic programs at the Jacobs School of Engineering were ranked in the top 10 programs for undergraduates in rankings released Sept. 13, 2021 by U.S. News and World Report.    Full Story


UC San Diego researchers make glycomics data AI-ready

September 8, 2021

UC San Diego researchers make glycomics data AI-ready

Researchers at UC San Diego have created a tool that allows glycomics datasets to be analyzed using explainable Artificial Intelligence (AI) systems and other machine learning approaches. Full Story


Ultrasound remotely triggers immune cells to attack tumors in mice without toxic side effects

August 12, 2021

Ultrasound remotely triggers immune cells to attack tumors in mice without toxic side effects

A new cancer immunotherapy pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue. The approach could make chimeric antigen receptor (CAR) T-cell therapy safer and effective at treating solid tumors. Full Story


New tool enables mapping of protein interaction networks at scale

August 3, 2021

New tool enables mapping of protein interaction networks at scale

Bioengineers at UC San Diego have developed a technology capable of revealing the network of interactions among thousands of proteins in a cell, in a single experiment. The tool allows researchers to map the protein-protein interaction network from their cells of interest within several weeks, without any specialized resources such as antibodies or premade gene libraries. Full Story


UC San Diego among six U.S. institutions in new Wu Tsai Human Performance Alliance

July 21, 2021

UC San Diego among six U.S. institutions in new Wu Tsai Human Performance Alliance

UC San Diego is one of six universities invited to participate in the Wu Tsai Human Performance Alliance, a scientific collaboration that aims to transform human health on a global scale through the discovery and translation of the biological principles underlying human performance. The UC San Diego arm of the Alliance is led by Andrew McCulloch, a professor in the departments of Bioengineering and Medicine. Full Story


Bio-inspired hydrogel protects the heart from post-op adhesions

June 18, 2021

Bio-inspired hydrogel protects the heart from post-op adhesions

A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents by a team of University of California San Diego researchers. The team of engineers, scientists and physicians also conducted a pilot study on porcine hearts, with promising results. They describe their work in the June 18, 2021 issue of Nature Communications.   Full Story


Titans of industry, academia team up to advance engineering in medicine

June 10, 2021

Titans of industry, academia team up to advance engineering in medicine

As the silos that once separated engineering and medicine continue to dissolve, there is a growing need on campus for facilities where engineers, physicians and medical researchers can work in the same physical research ecosystems. Pioneering bioengineer, professor Shu Chien, and his wife K.C., joined forces with Peter Farrell, founder of medical device company ResMed, to support this vision. Full Story


Undergraduate researchers earn Goldwater Scholarship

May 13, 2021

Undergraduate researchers earn Goldwater Scholarship

Three UC San Diego undergraduate students with impressive academic and research credentials were selected to receive the Goldwater Scholarship, designed to foster and encourage outstanding students to pursue research careers in the fields of the natural sciences, engineering and mathematics.  Full Story


Bioengineering student earns Strauss Scholarship

May 13, 2021

Bioengineering student earns Strauss Scholarship

UC San Diego bioengineering undergraduate Zina Patel was selected to receive the $15,000 Strauss Scholarship, awarded to outstanding students developing social change or public service projects. Full Story


UC San Diego Engineering Ranks #9 in U.S. News and World Report Best Engineering Schools Rankings

March 30, 2021

UC San Diego Engineering Ranks #9 in U.S. News and World Report Best Engineering Schools Rankings

For the second year in a row, the University of California San Diego Jacobs School of Engineering has ranked #9 in the nation in the influential U.S. News & World Report Rankings of Best Engineering Schools.    Full Story


New ways of looking inside living cells

March 29, 2021

New ways of looking inside living cells

From developing new imaging platforms, to asking new biological questions, and developing new disease diagnostics, UC San Diego bioengineering professor Lingyan Shi is pushing the boundaries of what's possible when we look inside living cells. Full Story


How to speed up muscle repair

March 17, 2021

How to speed up muscle repair

By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be triggered to accelerate muscle cell growth, providing new insights for developing therapies for muscle disease, injury and atrophy. Full Story


With gene therapy, scientists develop opioid-free solution for chronic pain

March 10, 2021

With gene therapy, scientists develop opioid-free solution for chronic pain

A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. By temporarily repressing a gene involved in sensing pain, the treatment increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness. Full Story