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Why are neuron axons long and spindly? Study shows they're optimizing signaling efficiency

July 11, 2018

Why are neuron axons long and spindly? Study shows they're optimizing signaling efficiency

A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are axons, the spindly arms extending from neurons that transmit information from neuron to neuron in the brain, designed the way they are? Full Story


Biosensor chip detects single nucleotide polymorphism wirelessly and with higher sensitivity

July 9, 2018

Biosensor chip detects single nucleotide polymorphism wirelessly and with higher sensitivity

A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and wirelessly send the results in real time to an electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology. The advance could lead to cheaper, faster and portable biosensors for early detection of genetic markers for diseases such as cancer. Full Story


Graduating students honored with Awards for Excellence

June 15, 2018

Graduating students honored with Awards for Excellence

Here are some highlights from the impressive resumes of the 2018 Jacobs School of Engineering student award winners, recognized by the IDEA Engineering Student Center and Dean Albert P. Pisano at the Ring Ceremony. Full Story


Engineering students and alumni sweep Triton Entrepreneur Night

June 7, 2018

Engineering students and alumni sweep Triton Entrepreneur Night

Two teams led by students and alumni of the Jacobs School of Engineering won big at Triton Entrepreneur Night, the signature event of The Basement—an undergraduate business incubator founded in 2015 with support from alumni. The teams competitively pitched their ideas, Shark Tank style, to a panel of esteemed investors and entrepreneurs.  Full Story


Engineering student leaders honored

May 24, 2018

Engineering student leaders honored

Top performing engineering student leaders were honored at the 9th annual Engineering Leadership Awards celebration on May 17. The event, presented by the Gordon Engineering Leadership Center at UC San Diego, recognizes undergraduate and graduate engineering students who demonstrate extraordinary leadership through their communication skills, teamwork abilities and implementation of technical solutions in competitions or real-world challenges. Full Story


You Can Eat That Fork

May 17, 2018

You Can Eat That Fork

Zhicong “Zack” Kong, a 2017 bioengineering alumnus from UC San Diego, created compostable, durable, edible cutlery that is unique for several reasons:the ingredients, a scalable manufacturing process and an innovative mold technology. Full Story


Study to Explore Whether Cannabis Compound Eases Severe Symptoms of Autism

May 1, 2018

Study to Explore Whether Cannabis Compound Eases Severe Symptoms of Autism

Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol (CBD), a non-psychoactive compound found in the cannabis plant, provides therapeutic benefit to children with severe symptoms of autism spectrum disorder (ASD).  The study, scheduled to launch in approximately one year, is funded by a $4.7 million gift from the Ray and Tye Noorda Foundation, in partnership with the Wholistic Research and Education Foundation. It represents the largest known private gift to date for medicinal cannabis research in the United States.  Full Story


April 24, 2018

Flames "On Edge" wins big at Research Expo

The research presented at Research Expo 2018 was “on fire” thanks to UC San Diego mechanical engineering graduate student Luca Carmignani. He took home the top prize at Research Expo for his work to understand the spread of fire over real-world 3D shapes. Full Story


Eight Jacobs School alumni recognized at UC San Diego's first 40 Under 40 awards

April 12, 2018

Eight Jacobs School alumni recognized at UC San Diego's first 40 Under 40 awards

From startup founders to VPs at major technology companies, eight alumni of the Jacobs School of Engineering were recognized in the first 40 Under 40 awards bestowed by the University of California San Diego. Full Story


Even DNA that Doesn't Encode Genes Can Drive Cancer

April 2, 2018

Even DNA that Doesn't Encode Genes Can Drive Cancer

Most of the human genome — 98 percent — is made up of DNA but doesn’t actually encode genes, the recipes cells use to build proteins. The vast majority of genetic mutations associated with cancer occur in these non-coding regions of the genome, yet it’s unclear how they might influence tumor development or growth. Now researchers at University of California San Diego have identified nearly 200 mutations in non-coding DNA that play a functional role in cancer. Each of the mutations could represent a new target in the search for cancer drugs. The study is published April 2, 2018 in Nature Genetics. Full Story


A wearable system to monitor the stomach's activity throughout the day

March 21, 2018

A wearable system to monitor the stomach's activity throughout the day

A team of researchers has developed a wearable, non-invasive system to monitor electrical activity in the stomach over 24 hours—essentially an electrocardiogram but for the gastro-intestinal (GI) tract.  Applications include monitoring GI activity for patients outside of a clinical setting, which cuts down costs. Monitoring for longer periods of time also increases the likelihood of capturing abnormal events.  Researchers detail their findings in the March 22 issue of Nature’s open access journal Scientific Reports. Full Story


Engineers Sweep Entrepreneur Challenge Startup Stage at Ignite

March 15, 2018

Engineers Sweep Entrepreneur Challenge Startup Stage at Ignite

Engineers showed up in force at the second annual Ignite Conference pitch competition at UC San Diego. Almost a third of the 29 startups pitching their innovative business ideas during the Entrepreneur Challenge-led elevator pitch competition were founded by engineers—including the first, second and third place winners. That’s right, it was an engineering clean sweep. Full Story


Engineers develop most efficient red-light-activated switch that can turn genes on and off in mammalian cells

March 12, 2018

Engineers develop most efficient red-light-activated switch that can turn genes on and off in mammalian cells

A team of researchers has developed a light-activated switch that can turn genes on and off in mammalian cells. This is the most efficient so-called “optogenetic switch” activated by red and far-red light that has been successfully designed and tested in animal cells—and it doesn’t require the addition of light sensing molecules from outside the cells.   Full Story


How a Yeast Cell Helps Crack Open the 'Black Box' Behind Artificial Intelligence

March 5, 2018

How a Yeast Cell Helps Crack Open the 'Black Box' Behind Artificial Intelligence

A research team recently developed what they call a “visible” neural network and used it to build DCell, a model of a functioning brewer’s yeast cell, commonly used as a model in basic research. To do this, they amassed all knowledge of cell biology in one place and created a hierarchy of these cellular components. Then they mapped standard machine learning algorithms to this knowledgebase. Full Story


New online tool gives 3D view of human metabolic processes

February 27, 2018

New online tool gives 3D view of human metabolic processes

A new computational resource called Recon3D provides a 3D view of genes, proteins and metabolites involved in human metabolism. Researchers used the tool to map disease-related mutations on proteins and also probed how genes and proteins change in response to certain drugs. The work provides a better understanding of disease-causing mutations and could enable researchers to discover new uses for existing drug treatments. Full Story


How Bacteria Steal Antibiotic-Resistant Genes

February 22, 2018

How Bacteria Steal Antibiotic-Resistant Genes

Researchers at the University of California San Diego Center for Microbiome Innovation have identified the mechanism by which a clinically relevant bacterium may gain antibiotic resistance, and have come up with a model for predicting the conditions under which it spreads. The findings, which establish a framework for understanding, quantifying and hopefully combating the emergence of superbugs, were published in a recent paper in eLife. Full Story


UC San Diego Bioengineering Student Wins Winston Churchill Scholarship

February 16, 2018

UC San Diego Bioengineering Student Wins Winston Churchill Scholarship

Aswini Krishnan, a fourth-year bioengineering major at the University of California San Diego, has been awarded a Winston Churchill Scholarship, one of the most prestigious and competitive awards available to American students pursuing science, mathematics and engineering fields. The award provides one year of funding to pursue a master’s degree at Winston Churchill College at the University of Cambridge. Krishnan is the fourth UC San Diego student to receive the award since the program’s inception in 1963.  Full Story


Researchers develop a remote-controlled cancer immunotherapy system

January 15, 2018

Researchers develop a remote-controlled cancer immunotherapy system

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells. Full Story


From Class to Clinic

January 11, 2018

From Class to Clinic

It’s not every day that an undergrad­uate class influences the way surgeons prepare for operations. But that’s exactly what happened with a fresh­man bioengineering class co-taught by then-PhD student Jason Caffrey ’11, MS ’13‚ and professor Robert Sah.  Full Story


Updated brain cell map connects various brain diseases to specific cell types

December 11, 2017

Updated brain cell map connects various brain diseases to specific cell types

Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer’s, Parkinson’s, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers have identified 35 different subtypes of neurons and glial cells and discovered which of these subtypes are most susceptible to common risk factors for different brain diseases. Full Story