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Bioengineers awarded $14M from NIH to build digital maps of brain, other organs at single-cell level

November 2, 2018

Bioengineers awarded $14M from NIH to build digital maps of brain, other organs at single-cell level

Kun Zhang, professor of bioengineering at the University of California San Diego Jacobs School of Engineering, has received $14 million in grants from the National Institutes of Health to build 3D, digital single-cell maps of the human brain and organs in the respiratory and urinary systems. The work aims to provide a deeper understanding of the functions and malfunctions of organs in the human body at the level of individual cells. Full Story


UC San Diego Signs MOU with Foundation for Biomedical Research and Innovation at Kobe

October 26, 2018

UC San Diego Signs MOU with Foundation for Biomedical Research and Innovation at Kobe

The University of California San Diego and the Foundation for Biomedical Research and Innovation at Kobe (FBRI) have entered into a five-year memo of understanding (MOU). The MOU was announced Oct. 19, 2018 in Japan at the 20thanniversary celebration of the Kobe Biomedical Innovation Cluster, of which FBRI is the core research institute.The MOU affirms a shared interest between UC San Diego and FBRI in cooperative biomedical research that will include joint research projects and publications, co-hosting seminars and workshops, and site visits. The primary contacts for the MOU are Dr. Shu Chien for UC San Diego and Dr. Ryuji Hiramatsu for FBRI. Full Story


Machine learning identifies antibiotic resistance genes in tuberculosis-causing bacteria

October 25, 2018

Machine learning identifies antibiotic resistance genes in tuberculosis-causing bacteria

Researchers have trained a machine learning algorithm to identify and predict which genes make infectious bacteria resistant to antibiotics. The approach was tested on strains of Mycobacterium tuberculosis—the bacteria that cause tuberculosis (TB) in humans. It identified 33 known and 24 new antibiotic resistance genes in these bacteria. The approach could be used to predict resistance in other infection-causing pathogens. Full Story


Color Block

October 1, 2018

Four researchers recognized for innovative and transformative work by NIH

Three researchers at the University of California San Diego have been selected to receive 2018 NIH Director’s New Innovator Awards. In addition, David Traver from the UC San Diego School of Medicine, has received an NIH Director’s Transformative award. Full Story


Engineering graduate students selected as Siebel Scholars

September 19, 2018

Engineering graduate students selected as Siebel Scholars

Five Jacobs School of Engineering graduate students working to improve immunology, cardiac health, blood transfusions and our understanding of the genome have been named 2019 Siebel Scholars. The Siebel Scholars program recognizes the most talented students in the world’s leading graduate schools of business, computer science, bioengineering and energy science. Full Story


UC San Diego clinician-engineer teams selected as 2018 Galvanizing Engineering in Medicine awardees

September 6, 2018

UC San Diego clinician-engineer teams selected as 2018 Galvanizing Engineering in Medicine awardees

Four clinician-engineer teams from UC San Diego have been selected to receive the 2018 Galvanizing Engineering in Medicine (GEM) awards. GEM, an initiative of UC San Diego Altman Clinical and Translational Research Institute (ACTRI) and UC San Diego Institute of Engineering in Medicine (IEM), brings engineers and clinicians together to develop innovative technologies that can be applied to solving challenging problems in medical care. This year’s projects address challenges in the areas of urology, telerobotic surgery, oncology, and spinal cord injuries. Full Story


Scientists discover a destructive mechanism that blocks the brain from knowing when to stop eating

August 22, 2018

Scientists discover a destructive mechanism that blocks the brain from knowing when to stop eating

An international team of researchers has uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity, called leptin resistance.They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal cells in the hypothalamus. This blocks leptin from binding to its receptors. This in turn keeps the neurons from signaling that your stomach is full and you should stop eating. This is the first time that a destructive molecular mechanism has been observed and described. Full Story


Bioengineers receive $12M grant from NIH to further research on building blocks of human metabolism

August 17, 2018

Bioengineers receive $12M grant from NIH to further research on building blocks of human metabolism

The University of California San Diego has received a $12 million, four-year grant from the National Institutes of Health to expand the Metabolomics Workbench, a searchable, interactive repository of data for all research in the field of metabolomics—the study of the small molecules called metabolites  that are found within cells and biological systems. The Metabolomics Workbench project, led by bioengineering professor Shankar Subramaniam at the Jacobs School of Engineering at UC San Diego, launched in 2012 with a $6 million grant from the NIH. This new infusion of funds will allow Subramaniam and colleagues to add a wide range of clinical data to the Workbench and take the project into the clinic itself. This in turn will allow researchers and physicians to develop better tools to diagnose diseases through metabolite markers in blood. Full Story


Medical mist could fight hospital-acquired infections

July 31, 2018

Medical mist could fight hospital-acquired infections

A team of engineers and physicians in San Diego have developed a device that diffuses potent disinfectants for airborne delivery. Notably, the device works on a range of disinfectants that have never been atomized before, such as Triethylene glycol, or TEG. In a study published in the August issue of Applied Microbiology and Biotechnology, the team used the device to atomize disinfectants onto environmental surfaces contaminated with bacteria and showed that it effectively eliminated 100 percent of bacteria that commonly cause hospital-acquired infections. In addition, atomized bleach solution, ethanol and TEG completely eliminated highly multi-drug resistant strains of bacteria including K. pneumoniae. Full Story


UC San Diego bioengineers bring functional genomics data into personal websites

July 23, 2018

UC San Diego bioengineers bring functional genomics data into personal websites

Bioengineers at the University of California San Diego have developed a programming library that can enable researchers to effortlessly visualize and share genomic data on their personal websites. The new open source programming library, named “GIVE” (genomic interaction visualization engine), can be used by non-experts and in many cases even eliminates the need to write any computer codes. Full Story


High vinculin levels help keep aging fruit fly hearts young

July 17, 2018

High vinculin levels help keep aging fruit fly hearts young

A new discovery in how heart muscles maintain their shape in fruit flies sheds light on the crucial relationship between cardiac function, metabolism, and longevity. Researchers from the University of California San Diego discovered that maintaining high levels of the protein vinculin—which sticks heart muscle cells to one another—confers health benefits to fruit flies. Their work shows that fruit flies bred to produce 50 percent more vinculin enjoyed better cardiovascular health and lived a third of their average life span longer.  Full Story


Why are neuron axons long and spindly? Study shows they're optimizing signaling efficiency

July 11, 2018

Why are neuron axons long and spindly? Study shows they're optimizing signaling efficiency

A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are axons, the spindly arms extending from neurons that transmit information from neuron to neuron in the brain, designed the way they are? Full Story


Biosensor chip detects single nucleotide polymorphism wirelessly and with higher sensitivity

July 9, 2018

Biosensor chip detects single nucleotide polymorphism wirelessly and with higher sensitivity

A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and wirelessly send the results in real time to an electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology. The advance could lead to cheaper, faster and portable biosensors for early detection of genetic markers for diseases such as cancer. Full Story


Graduating students honored with Awards for Excellence

June 15, 2018

Graduating students honored with Awards for Excellence

Here are some highlights from the impressive resumes of the 2018 Jacobs School of Engineering student award winners, recognized by the IDEA Engineering Student Center and Dean Albert P. Pisano at the Ring Ceremony. Full Story


Engineering students and alumni sweep Triton Entrepreneur Night

June 7, 2018

Engineering students and alumni sweep Triton Entrepreneur Night

Two teams led by students and alumni of the Jacobs School of Engineering won big at Triton Entrepreneur Night, the signature event of The Basement—an undergraduate business incubator founded in 2015 with support from alumni. The teams competitively pitched their ideas, Shark Tank style, to a panel of esteemed investors and entrepreneurs.  Full Story


Engineering student leaders honored

May 24, 2018

Engineering student leaders honored

Top performing engineering student leaders were honored at the 9th annual Engineering Leadership Awards celebration on May 17. The event, presented by the Gordon Engineering Leadership Center at UC San Diego, recognizes undergraduate and graduate engineering students who demonstrate extraordinary leadership through their communication skills, teamwork abilities and implementation of technical solutions in competitions or real-world challenges. Full Story


You Can Eat That Fork

May 17, 2018

You Can Eat That Fork

Zhicong “Zack” Kong, a 2017 bioengineering alumnus from UC San Diego, created compostable, durable, edible cutlery that is unique for several reasons:the ingredients, a scalable manufacturing process and an innovative mold technology. Full Story


Study to Explore Whether Cannabis Compound Eases Severe Symptoms of Autism

May 1, 2018

Study to Explore Whether Cannabis Compound Eases Severe Symptoms of Autism

Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol (CBD), a non-psychoactive compound found in the cannabis plant, provides therapeutic benefit to children with severe symptoms of autism spectrum disorder (ASD).  The study, scheduled to launch in approximately one year, is funded by a $4.7 million gift from the Ray and Tye Noorda Foundation, in partnership with the Wholistic Research and Education Foundation. It represents the largest known private gift to date for medicinal cannabis research in the United States.  Full Story


April 24, 2018

Flames "On Edge" wins big at Research Expo

The research presented at Research Expo 2018 was “on fire” thanks to UC San Diego mechanical engineering graduate student Luca Carmignani. He took home the top prize at Research Expo for his work to understand the spread of fire over real-world 3D shapes. Full Story


Eight Jacobs School alumni recognized at UC San Diego's first 40 Under 40 awards

April 12, 2018

Eight Jacobs School alumni recognized at UC San Diego's first 40 Under 40 awards

From startup founders to VPs at major technology companies, eight alumni of the Jacobs School of Engineering were recognized in the first 40 Under 40 awards bestowed by the University of California San Diego. Full Story