News Archive
January 24, 2014
UC San Diego Highlighted in Governor's State of the State Address
As Governor Edmund G. Brown Jr. delivered his annual State of the State address to the Legislature yesterday, he highlighted the University of California, San Diego as a leader in developing medical and scientific advances. In prepared remarks, Gov. Brown noted, “Four out of the world’s 20 leading academic bioscience institutions are located here in California: UCSF and Berkeley, UCLA, Stanford and UC San Diego. Just as California has led the way with stem cell research, so too can we pioneer the new field of precision medicine which uses genomics, medical devices, computer sciences and other fields to treat individual patients, instead of broad populations.” Full Story
January 14, 2014
Single-Cell Genome Sequencing Gets Better
Bioengineers at the Jacobs School have created a better way to sequence genomes from individual cells. The breakthrough, which relies on microwells just 12 nanoliters in volume (see image below), is one of many recent "omics" innovations from researchers across the Jacobs School and UC San Diego. The single-cell genome sequencing advance from Kun Zhang's lab could help researchers understand what causes Alzheimer's disease. The work could also enable scientists to identify tough-to-culture microbes living in ocean water and within the human body-by probing single cells. Full Story
January 9, 2014
How to Manage Mobile Medical App Development Under FDA Regulation
A consortium of six leading universities, more than a dozen industry trade associations and professional societies, and the U.S. Food & Drug Administration announced their unprecedented collaboration to develop a series of educational programs designed to help mobile app developers learn about FDA requirements for producing higher risk medical apps as well as the business issues associated with entering this space.Called the “MMA Roadshow: Managing App Development under FDA Regulation,” the four-hour workshops are scheduled over several months across the country, including Jan. 27 at the University of California, San Diego. Full Story
January 6, 2014
Biomaterials Get Stem Cells to Commit to a Bony Future
With the help of biomimetic matrices, a research team led by bioengineers at the University of California, San Diego has discovered exactly how calcium phosphate can coax stem cells to become bone-building cells. This work is published in the Proceedings of the National Academy of Sciences the week of Jan. 6, 2014. Full Story
December 13, 2013
2013: The Year in Review
From the largest alumni gift in the campus’ history, which went to the Department of Computer Science and Engineering, to the arrival of Dean Al Pisano, it’s been a busy year here at the Jacobs School of Engineering. The school produced many research milestones, from a Google map of the human metabolism to the world’s first zoomable contact lens. Students got into the action too and UC San Diego became the first university to design, build and test a 3D-printed rocket engine. Here are some of the most memorable stories of the year—but not all: the list would be too long. Full Story
November 25, 2013
Bioengineering Professor Among Six UC San Diego Faculty Named 2013 AAAS Fellows
Six professors at the University of California, San Diego have been named 2013 Fellows of the American Association for the Advancement of Science, the nation’s largest general science organization. Full Story
November 18, 2013
New Models Predict Where E. coli Strains Will Thrive
Bioengineers at the University of California, San Diego have used the genomic sequences of 55 E. coli strains to reconstruct the metabolic repertoire for each strain. Surprisingly, these reconstructions do an excellent job of predicting the kind of environment where each strain will thrive, the researchers found. Their analysis, published in the Nov. 18, 2013 early edition of the Proceedings of the National Academy of Sciences, could prove useful in developing ways to control deadly E. coli infections and to learn more about how certain strains of the bacteria become virulent. Full Story
November 12, 2013
Single-Cell Genome Sequencing Gets Better
Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters. Full Story
October 30, 2013
Genomatica Among 100 Companies Highlighted for Economic Boost of Research
Two innovative UC San Diego spinoffs are among the 100 companies cited by The Science Coalition in a new report touting the positive economic payoff of federally funded university research. Genomatica, a biotechnology company that grew from research conducted in Bernhard Palsson’s laboratory at UC San Diego; and Senomyx, a provider of flavor ingredients for the food and beverage industries that arose from research conducted by Charles Zuker at UC San Diego, help demonstrate how support of basic and applied research at American universities pays strong economic dividends. Full Story
October 22, 2013
Bioinformatics Breakthrough: High Quality Transcriptome from as Few as Fifty Cells
Bioengineers from the University of California, San Diego have created a new method for analyzing RNA transcripts from samples of 50 to 100 cells. The approach could be used to develop inexpensive and rapid methods for diagnosing cancers at early stages, as well as better tools for forensics, drug discovery and developmental biology. Full Story
October 17, 2013
Bioengineers Team with High School Students to Study Age-Related Heart Disease
Bioengineering professor Adam Engler recently launched a six-week fruit fly experiment with a group of 11th grade biology students in a study of age-related heart disease. The question driving the project is whether genetic mutations in the heart, mutations that are common in humans as we age and that are correlated with poor heart function, also contribute to a shortened lifespan? Full Story
October 8, 2013
Bioengineers uncover cause, treatment for insulin resistance in shock patients
Bioengineers at the University of California, San Diego have discovered that insulin resistance in shock patients is caused by the leakage of powerful digestive enzymes from the small intestine that eat away and destroy the insulin receptor in cells. Reporting in the journal Shock, the team has also found a way to stop these enzymes’ destructive path by blocking them in the intestine, where they are normally used to digest food. The research team includes Frank DeLano, lead investigator, and co-investigator Geert Schmid-Schönbein, professor and chair of bioengineering at UC San Diego Jacobs School of Engineering. Doctors have long known that trauma patients going into shock are at risk of developing acute insulin resistance, leading to hyperglycemia. The pancreas releases insulin to deliver glucose to cells to convert into energy for the body. When cells are unable to process insulin properly, a condition known as insulin resistance, blood sugars rise and the pancreas releases more insulin, compounding the problem. Until now, doctors have not known what mechanism causes insulin resistance to develop in shock patients or how to treat it. Full Story
October 1, 2013
Computer Scientists Develop New Approach to Sort Cells Up to 38 Times Faster
A team of engineers led by computer scientists at the University of California, San Diego, has developed a new approach that marries computer vision and hardware optimization to sort cells up to 38 times faster than is currently possible. The approach could be used for clinical diagnostics, stem cell characterization and other applications. Full Story
September 18, 2013
'Wildly Heterogeneous Genes'
Cancer tumors almost never share the exact same genetic mutations, a fact that has confounded scientific efforts to better categorize cancer types and develop more targeted, effective treatments. In a paper published in the September 15 advanced online edition of Nature Methods, researchers at the University of California, San Diego propose a new approach called network-based stratification (NBS), which identifies cancer subtypes not by the singular mutations of individual patients, but by how those mutations affect shared genetic networks or systems. Full Story
September 17, 2013
Bioengineers Researching Smart Cameras and Sensors that Mimic, Exceed Human Capability
University of California, San Diego bioengineering professor Gert Cauwenberghs has been selected by the National Science Foundation to take part in a five-year, multi-institutional, $10 million research project to develop a computer vision system that will approach or exceed the capabilities and efficiencies of human vision. Full Story
September 4, 2013
UC San Diego Bioengineering and IEM Programmer Named 2013 Presidential Innovation Fellow
Justin Grevich, a web developer and systems administrator in bioengineering and the Institute of Engineering in Medicine, has been named a 2013 Presidential Innovation Fellow. Full Story
August 12, 2013
New electron beam writer enables next-gen biomedical and information technologies
The new electron beam writer housed in the Nano3 cleanroom facility at the Qualcomm Institute is important for electrical engineering professor Shadi Dayeh’s two major areas of research. He is developing next-generation, nanoscale transistors for integrated electronics; and he is developing neural probes that have the capacity to extract electrical signals from individual brain cells and transmit the information to a prosthetic device or computer. Achieving this level of signal extraction or manipulation requires tiny sensors spaced very closely together for the highest resolution and signal acquisition. Enter the new electron beam writer. Full Story
July 29, 2013
Conference for African-American Researchers in Mathematics Connects Students to Mentors
For Lauren Crudup, a third-year bioengineering student at the University of California, San Diego, the Conference for African-American Researchers in the Mathematical Sciences (CAARMS) presented a unique opportunity to learn just how applicable mathematics is in the real-world—especially compared to the pure mathematics she learned in high school and earlier undergraduate courses. Full Story
June 27, 2013
Faculty Invited to Exclusive Symposium for 'Creative Young Engineers'
Jacobs School of Engineering professors Karen Christman and Gert Lanckriet are among 81 of the nation’s most “creative young engineers” selected to attend this year’s U.S. Frontiers of Engineering Symposium by the National Academy of Engineering. Participation in the event is by invitation-only to engineers between the ages of 30-45 who have “demonstrated accomplishment in engineering research and technical work with recognizable contributions to advancing the frontiers of engineering,” according to an NAE announcement. Full Story
June 21, 2013
Technology-Enhanced Learning: From Campus to the World
The academic landscape is changing rapidly, due in no small part to recent advances in technologies to enable, enhance and deliver teaching and learning to a worldwide audience. At the University of California, San Diego, administrators and faculty are particularly focused on using technology to transform the undergraduate learning experience (saving money in the process). They’re doing this in the context of the UC San Diego Education Initiative, as well as the Technology-Enhanced Learning (TEL) Initiative jump-started by Calit2’s Qualcomm Institute. Both programs are helping to formulate a way forward for the campus, with the Education Initiative focused on policy, and the TEL Initiative experimenting with various models of online learning. Full Story