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August 20, 2012

Program trains professionals in medical device engineering

Dan Braun earned a bachelor’s in mechanical engineering at the University of California, San Diego in 2006.  Five years later he came back to enroll in the inaugural class of the UC San Diego Jacobs School of Engineering’s Master of Advanced Study Program in Medical Device Engineering. The cross-disciplinary program is designed to train working professionals to apply their engineering know-how and workforce experience to a new career in one of the region’s fastest growing technology sectors. Full Story


Computer models calculate systems-wide costs of gene expression

August 7, 2012

Computer models calculate systems-wide costs of gene expression

Bioengineers at the University of California, San Diego have developed a method of modeling, simultaneously, an organism’s metabolism and its underlying gene expression.  In the emerging field of systems biology, scientists model cellular behavior in order to understand how processes such as metabolism and gene expression relate to one another and bring about certain characteristics in the larger organism. Full Story


Gene Mutations Cause Massive Brain Asymmetry

June 29, 2012

Gene Mutations Cause Massive Brain Asymmetry

Hemimegalencephaly is a rare but dramatic condition in which the brain grows asymmetrically, with one hemisphere becoming massively enlarged. Though frequently diagnosed in children with severe epilepsy, the cause of hemimegalencephaly is unknown and current treatment is radical: surgical removal of some or all of the diseased half of the brain. In a paper published in the June 24, 2012 online issue of Nature Genetics, a team of doctors and scientists, led by researchers at the University of California, San Diego School of Medicine and the Howard Hughes Medical Institute, say de novo somatic mutations in a trio of genes that help regulate cell size and proliferation are likely culprits for causing hemimegalencephaly, though perhaps not the only ones. Full Story


Flexible Electronics Push Frontier in Neonatal Neuroscience

June 28, 2012

Flexible Electronics Push Frontier in Neonatal Neuroscience

Anyone who has seen a newborn in a hospital neonatal intensive care unit (NICU) knows the image is shocking. Wires and electrodes designed to monitor vital signals such as heart rate, brain signals and blood oxygen levels are taped over the frail newborn’s head, face and body. Skin-to-skin contact between mom and baby that doctors say all newborns need to develop a sense of security and bonding becomes challenging, if not impossible. Parents seeing their precious baby this way may also feel terrified and helpless. A new study at the University of California, San Diego will test whether all of those bulky electronics could be replaced with a stamp-sized wearable patch of tiny circuits, sensors, and wireless transmitters that sticks to the skin like a temporary tattoo, stretching and flexing with the skin while maintaining high performance. Full Story


Medical Technologies Dominate UC San Diego Entrepreneur Challenge

June 18, 2012

Medical Technologies Dominate UC San Diego Entrepreneur Challenge

The pitches at the UC San Diego Entrepreneur Challenge included technologies to cure cancer, brain-computer interfaces for patients without speech, an automated portfolio management system, sensor assisted orthopedic surgery, garbage compactors, and an enhanced dental implant.  Full Story


Students Showcase Eureka Moments at Undergraduate Research Expo

June 7, 2012

Students Showcase Eureka Moments at Undergraduate Research Expo

  A new acne medicine; a better way to simulate the collapse of supernovae; and a better way to visualize chromosomes: these were just some of the research posters on display at EUReKA, an undergraduate research expo that took place Friday at the Jacobs School of Engineering. Full Story


Grand Challenges Explorations Grant  Funds Groundbreaking Health Research

May 8, 2012

Grand Challenges Explorations Grant Funds Groundbreaking Health Research

The University of California, San Diego Jacobs School of Engineeringannounced today that it is a Grand Challenges Explorationswinner, an initiative funded by the Bill & Melinda Gates Foundation.  Bioengineering Professor Todd Coleman, in collaboration with Materials Science and Engineering Professor John A. Rogers at the University of Illinois at Urbana-Champaign,will pursue an innovative global health and development research project, titled “Epidermal Electronics for Continuous Pregnancy Monitoring.” Full Story


'Blinking microbubbles' for early cancer screening take grand prize at Research Expo 2012

April 20, 2012

'Blinking microbubbles' for early cancer screening take grand prize at Research Expo 2012

Carolyn Schutt, a Ph.D student in bioengineering at the University of California, San Diego is developing a new imaging technique that would enable highly-sensitive light imaging deeper inside the body, improving the way we diagnose breast cancer. Schutt’s research received the grand prize April 12 at the UC San Diego Jacob School of Engineering Research Expo 2012. Full Story


Research Expo: Access Game-Changing Research and Technologies

April 2, 2012

Research Expo: Access Game-Changing Research and Technologies

There are many ways to engage with the Jacobs School of Engineering at the University of California, San Diego, but the only way to get face time with 230-plus graduate students working on game-changing research in a single afternoon is to attend Research Expo on April 12. Research Expo provides a glimpse into the engineering future – a future that will touch all of San Diego’s technology sectors. With $146.4 million in research expenditures in fiscal year 2010-2011, there’s a lot to look at. Full Story


Faculty researchers share their experiences turning discoveries into marketable products

March 27, 2012

Faculty researchers share their experiences turning discoveries into marketable products

Four engineering faculty members with technology transfer success stories discussed the challenges of the commercialization process during a March 14 dinner celebrating the 10th anniversary of the von Liebig Center for Entrepreneurism and Technology Advancement. The von Liebig Center offers seed funding and advisory services and is part of the Jacobs School of Engineering at the University of California, San Diego. Full Story


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March 12, 2012

A lifetime of research may be leading to a life-saving treatment for shock

A 200-patient Phase 2 clinical pilot study will be initiated this month to test the efficacy and safety of a new use, and method of administering, an enzyme inhibitor  for critically ill patients developed by University of California, San Diego Bioengineering Professor Geert Schmid-Schönbein. Conditions expected to qualify for the study include new-onset sepsis and septic shock, post-operative complications, and new-onset gastrointestinal bleeding. Full Story


Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering

March 5, 2012

Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering

University of California, San Diego bioengineers have developed a self-healing hydrogel that binds in seconds, as easily as Velcro, and forms a bond strong enough to withstand repeated stretching. The material has numerous potential applications, including medical sutures, targeted drug delivery, industrial sealants and self-healing plastics, a team of UC San Diego Jacobs School of Engineering researchers reported March 5 in the online Early Edition of the Proceedings of the National Academy of Sciences. Full Story


Injectable Gel Could Repair Tissue Damaged by Heart Attack

February 21, 2012

Injectable Gel Could Repair Tissue Damaged by Heart Attack

University of California, San Diego researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks. Full Story


New Method Makes Culture of Complex Tissue Possible in any Lab

February 13, 2012

New Method Makes Culture of Complex Tissue Possible in any Lab

Scientists at the University of California, San Diego have developed a new method for making scaffolds for culturing tissue in three-dimensional arrangements that mimic those in the body. This advance, published online in the journal Advanced Materials, allows the production of tissue culture scaffolds containing multiple structurally and chemically distinct layers using common laboratory reagents and material Full Story


UC San Diego Jacobs School of Engineering Faculty Elected to National Academy of Engineering

February 9, 2012

UC San Diego Jacobs School of Engineering Faculty Elected to National Academy of Engineering

Three faculty members in the Department of Mechanical and Aerospace Engineering at the University of California, San Diego Jacobs School of Engineering have been elected to the National Academy of Engineering. Peter C. Farrell, founder, chairman and CEO of ResMed, and a member of the Council of Advisors of the Dean of the Jacobs School, also was elected to the academy. Full Story


Need Muscle for a Tough Spot? Turn to Fat Stem Cells, UC San Diego Researchers Say

January 26, 2012

Need Muscle for a Tough Spot? Turn to Fat Stem Cells, UC San Diego Researchers Say

Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle cells. The new research appears in the journal Biomaterials.  Full Story


Researchers Create Living 'Neon Signs' Composed of Millions of Glowing Bacteria

December 19, 2011

Researchers Create Living 'Neon Signs' Composed of Millions of Glowing Bacteria

  In an example of life imitating art, biologists and bioengineers at UC San Diego have created a living neon sign composed of millions of bacterial cells that periodically fluoresce in unison like blinking light bulbs. Their achievement, detailed in this week’s advance online issue of the journal Nature, involved attaching a fluorescent protein to the biological clocks of the bacteria, synchronizing the clocks of the thousands of bacteria within a colony, then synchronizing thousands of the blinking bacterial colonies to glow on and off in unison. Full Story


New Shu Chien Lab in New Research Building to Investigate Best Environment to Grow Stem Cells

December 7, 2011

New Shu Chien Lab in New Research Building to Investigate Best Environment to Grow Stem Cells

  Bioengineering Professor Shu Chien, who recently received a National Medal of Science at the White House, will have a laboratory in the new Sanford Consortium for Regenerative Medicine building. Chien’s lab will be dedicated to further developing a technology that allows scientists to identify the best environments to grow stem cells. Creating these environments requires mixing many proteins in a wide range of combinations. The new technology allows researchers to test hundreds of them at once. Full Story


Jacobs School Recruiting for 10 Positions in 2011-12

November 28, 2011

Jacobs School Recruiting for 10 Positions in 2011-12

  The Jacobs School of Engineering at UC San Diego currently is recruiting for 10 open faculty positions in the 2011-12 academic year. The positions fall within three strategic research focus areas identified by the school: energy, sustainability and environment; engineering in medicine; and information technology and applications. An additional position focuses on the applicants’ contributions to diversity, in addition to research and scholarship.  Full Story


New UC San Diego Bioengineering Professor Uncovers Cancer Metabolism Insights

November 21, 2011

New UC San Diego Bioengineering Professor Uncovers Cancer Metabolism Insights

Research from a new member of the bioengineering faculty at the UC San Diego Jacobs School of Engineering demonstrates that our cells metabolize nutrients in a very different manner than has long been thought. According to new research published in the journal Nature by Christian Metallo, an Assistant Professor in the Department of Bioengineering, cells growing under conditions similar to those inside tumors prefer to convert amino acids to lipids rather than carbohydrates.  Full Story